Ankylosing spondylitis is a chronic inflammatory condition that primarily affects the spine and sacroiliac joints, causing persistent stiffness, back pain, and reduced mobility. Early diagnosis helps slow structural damage, while treatment focuses on reducing inflammation, preserving spinal function, and improving quality of life. A combination of medical management, targeted exercise, and osteopathic techniques can help manage symptoms and enhance daily function. Understanding the condition empowers patients to take an active role in long-term care and self-management.